腺病毒(AdV)包装

 

重组腺病毒(AdV)是一种复制缺陷的腺病毒载体系统,在基因治疗、基础生命科学研究等领域被广泛应用。目前常用的腺病毒载体基于人腺病毒5型(Ad5),其基因组是36 kb长的线性双链DNA。腺病毒可通过自身的纤维(fiber)和细胞表面的受体结合被内吞进入细胞,然后从内吞体(endosome)转移到细胞质和细胞核内,借助细胞的转录和翻译机器启动病毒的复制组装。一个完整的病毒生活周期会引发细胞死亡从而释放出病毒粒子。

 

XIANBINGDUYOURUXIATEDIAN:

●  GANRANFANWEIGUANG:XIANBINGDUKESHIYONGYUPUTONGXIBAOXIDEGANRAN,YEKEYONGYUXUANFUXIBAO、YUANDAIXIBAODENG

●  高效:腺病毒的滴度可高达1011PFU/ml,感染效率高,可感染悬浮细胞、原代细胞等

●  ZAITIRONGLIANGDA:XIANBINGDUDEZAITIRONGLIANGJIAODA,ZUIGAOKEDA8kb

 

 

 

汉恒生物提供腺病毒相关服务:

 

●  CHANGGUIJIYINGUOBIAODA/GANRAOXIANBINGDUBAOZHUANG

●  miRNA sponge/antagoXIANBINGDU

●  circRNA/LncRNAGUOBIAODAHEGANRAOXIANBINGDU

●  CRISPR/Cas9XIANBINGDUDINGZHI

●  XIANBINGDUCHUNHUAFUWU

●  XIANBINGDUXIANHUOCHANPIN

 

 

产品分类

 

●  PUTONGAd5ZHONGZUXIANBINGDU-SHIYONGPUTONGXIBAOXIGANRAN;

●  XUANFUXIBAOZHUANYONGXIANBINGDU-ZHUANWEIXUANFUXIBAOTESHUSHEJI,JIANRONGPUTONGXIBAOHEYUANDAIXIBAO,XIAOLVGENGGAO;

 

 

汉恒腺病毒优势:

 

● GUONEIXIANBINGDUSHICHANGZHANYOULVDIYI

● DUOCIRONGDENGCELLDENGDINGJIQIKAN

● DIXIBAODUXING(CHAOSULIXINCHUNHUAGONGYI)

● WUZHIYUANTIWURAN

● WUNEIDUSU、WAIYUANWEISHENGWU,WUSUANSUHEZHUCANLIU

● DIDUKEGAODA109TU/mL

● YIKEHUWEIZHONGXINDEQIANGDASHOUHOUFUWUTIXI

● Admax包装系统,滴度可高达1011PFU/mL

● PANGDADEXIANBINGDUXIANHUOKU

 

 

为什么选择汉恒?

 

● ZHUANZHUTIGONGBINGDUBAOZHUANGFUWUSHINIAN

● XIANBINGDUSHICHANGZHANYOULVGAODA60%,MANBINGDUAAVZHANYOULVLIANXUSHUNIANGUONEIQIANSAN

● SHANGQIANPIANSCIQIKANYINYONG,BAOKUOCELL、Nature MedicineDENGDINGJIQIKAN

● YINIANYOU10000+KEHUHEHANHENGHEZUO

● ISO9001RENZHENGDEZHILIANGTIXI,YANGEDEBINGDUCHUNHUAGONGYI

● ZHUNSHIJIAOFULVLIANXUSANNIANCHAO98%

● WANSHANDEKEHUFUWUTIXI,JISHUZHICHI、XIANGMUGENJIN、SHOUHOUFUWUHUODEKEHUYIZHIHAOPING,QUEBAONINDINGGOUWUYOU

 

 

腺病毒感染实例:

 

● XIANBINGDUGANRANPUTONGTIEBIXIBAO

 

mRFP-GFP-LC3ZISHISHUANGBIAOXIANBINGDUGANRANHCT116HEHT29, HANHENGKEHU2017NIANFABIAOYUCELL,IF>30

 

● XIANBINGDUGANRANYUANDAIXIBAO