环状RNA病毒载体

 

环状RNA简介

 

circRNAs(Circular RNAs,HUANXINGRNAFENZI)SHIYILEIBUJUYOU5' MODUANMAOZIHE3' MODUANpoly(A)WEIBA、BINGYIGONGJIAJIANXINGCHENGHUANXINGJIEGOUDEFEIBIANMARNAFENZI。circRNASHIQUBIEYUCHUANTONGXIANXINGRNADEYILEIXINXINGRNA,JUYOUBIHEHUANZHUANGJIEGOU,DALIANGCUNZAIYUZHENHEZHUANLUZUZHONG。DABUFENDEHUANZHUANGRNASHIYOUWAIXIANZIXULIEGOUCHENG,ZAIBUTONGDEWUZHONGZHONGJUYOUBAOSHOUXING,TONGSHICUNZAIZUZHIJIBUTONGFAYUJIEDUANDEBIAODATEYIXING。YOUYUHUANZHUANGRNADUIHESUANMEIBUMINGAN,SUOYIBIXIANXINGRNAGENGWEIWENDING,ZHEISHIDEHUANZHUANGRNAZAIZUOWEIXINXINGLINCHUANGZHENDUANBIAOJIWUDEKAIFAYINGYONGSHANGJUYOUMINGXIANYOUSHI。

 

HANHENGSHENGWUWEIBIAODAHUANZHUANGRNAZAIMANBINGDU(Lentivirus)、XIANBINGDU(Adenovirus)HEXIANXIANGGUANBINGDU(Adeno associated virus)DENGGONGJUBINGDUZAITISHANGYINRUDUJIAYANFADEJIYINHUANHUABIAODAKUANGJIA,SHIHUANZHUANGRNALIANRUZAITIHOUNENGZAITIWAIGAOXIAOLVBIAODA,BINGBAOZHENGCHARUDEMUDEHUANZHUANGRNAPIANDUANZHENGQUEHUANHUA。

 

 

环状RNA的类型

 

 


 

 

 

TU1. TONGYIJIYINWEIZHIKEYICHANSHENGBUTONGLEIXINGDEHUANZHUANGRNA

 

 

汉恒circRNA QPCR引物

         

HANHENGTUANDUIYONGYOUZUICHENGSHUDEcircRNAYINWUSHEJIYUcircRNA-QPCRYANZHENGJISHU,QUFENCHENGHUANYUWEICHENGHUANRNA。 

 

 

环状RNA的功能

 

1. HUANZHUANGRNAKEYIZUOWEI“sponge”HAIMIANXIFUmiRNA,YIZHIQIGONGNENG

2. circRNATONGGUOJIANJIHUBUPEIDUIZHIJIEDIAOKONGQITARNASHUIPING

3. circRNANENGYUDANBAIZHIJIEHE,YIZHIDANBAIZHIHUOXING、MUJIDANBAIZHIFUHETIDEZUFENHUODIAOKONGDANBAIZHIDEHUOXING

 

 

汉恒提供环状RNA病毒包装服务

 

 

 

 

环状RNA病毒载体构建服务

 

 

pHBAd-ciRHUANZHUANGRNAXIANBINGDUZAITI

 

 

 

pHBAd-ciRHUANZHUANGRNAMANBINGDUZAITI

 

 

 

 

pHBAd-ciRHUANZHUANGRNAXIANXIANGGUANBINGDUZAITI

 

 

汉恒研究中心研究人员为您提供多种circRNA研究工具与解决方案

 

circRNA功能与重要性越来越受到重视,不管是生理、病理还是biomarker。汉恒生物经验丰富的circRNA研究团队,为您提供circRNA研究工具,参与定制您的天博电竞解决方案。

 

 

参考文献

 

1、Role of the microRNA, miR‐206, and its target PIK3C2α in endothelial progenitor cell function–potential link with coronary artery disease;
 (2015年发表于FEBS J.,作者:Xie Y)
 
2、A novel role of microRNA 17-5p in the modulation of circadian rhythm;
 (2016年发表于Sci Rep,作者:Ji-Min Cao)

 

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